New Directions in Single Cell Analysis

Technologies, data analytical approaches and biomedical / clinical applications.

Organisers: Wolfgang Huber, Niko Beerenwinkel, John Marioni and Oliver Stegle

Dates

28 and 29 August: Scientific Workshop
27 August, 13:00h – 18:00h: satellite meeting for the SOUND consortium

Venue

BioQuant
Im Neuenheimer Feld 267
Ruprecht-Karls-Universität Heidelberg
Heidelberg

How to get to BioQuant
By car:
Coming from the motorway (A 656): Turn left towards “Chirurgie” at the end of the Autobahn. Having crossed the Neckar on Ernst-Waltz-Brücke follow Berliner Straße. At the 2nd traffic light (“Shell” gas station & “Bunsengymnasium”) turn left towards Neuenheimer Feld (BioQuant 267).

By public transport:
From main railway station (Hauptbahnhof): Take either the tram number 24 (direction Handschuhsheim) or the number 21 (direction Technologiepark) and get off at the “Bunsengymnasium” stop.
From Heidelberg downtown (Bismarckplatz): Take the bus number 31 towards “Neuenheim, Chirurgische Klinik” and get off at the “Bunsengymnasium” bus stop.

Confirmed speakers

  • Simon Anders, ZMBH Heidelberg
  • Tim Becker, Broad Institute of MIT and Harvard, Cambridge
  • Michael Boutros, DKFZ Heidelberg
  • Laleh Haghverdi, EMBL Heidelberg
  • Thomas Höfer, DKFZ Heidelberg
  • Smita Krishnaswamy, Yale School of Medicine, USA
  • Aaron Lun, Cancer Research UK Cambridge Institute
  • Svetlana Ovchinnikova, ZMBH Heidelberg
  • Lucas Pelkmans, University of Zurich
  • Wolf Reik, Babraham Institute Cambridge
  • Charlotte Soneson, University of Zurich
  • Oliver Stegle, EMBL Heidelberg
  • Barbara Treutlein, Max Planck Institute for Evolutionary Anthropology, Leipzig
  • Britta Velten, EMBL Heidelberg
  • Lars Velten, EMBL Heidelberg

Registration

Registration for this workshop is closed and the event is fully booked. Spontaneous registrations on site are not possible.

Programme

Tuesday, 28 August 2018

09:00 – 09:10 Welcome. Organisers
09:10 – 9:50 Multiplexed protein maps link subcellular organization to cellular states. Lucas Pelkmans
9:50 – 10:30 Manifold learning yields insight into complex cellular state space.
Smita Krishnaswamy
10:30 – 11:00 Coffee break
11:00 – 11:40 Extendable benchmarks and reproducible exploration for scRNA-seq data. Charlotte Soneson
11:40 – 12:20 From Targeting Diseases to Characterizing Asthma. Tim Becker
12:20 – 13:20 Lunch
13:20 – 14:00 Reconstructing cellular transitions using single cell transcriptomics.
Barbara Treutlein
14:00 – 14:40 Combining somatic heterogeneity with scRNA-sew. Oliver Stegle
14:40 – 15:00 Coffee break
15:00 – 15:40 Batch correction in scRNA-seq data. Laleh Haghverdi
15:40 – 15:50 Break
15:50 – 17:00 Tutorial: Visual interactive exploration of omics data.
Simon Anders and Svetlana Ovchinnikova
17:00 – 19:00 Free time
19:00 Dinner (for the SOUND consortium and invited speakers only)

Wednesday, 29 August 2018

9:00 – 9:40 Single cell epigenome landscape of mammalian development and ageing. Wolf Reik
9:40 – 10:20 Mapping context-dependent genetic circuits of cells. Michael Boutros
10:20 – 10:50 Coffee break
10:50 – 11:30 DNA barcoding to decode hematopoietic development. Thomas Hoefer
11:30 – 12:10 Spatial transcriptomics reveals design principles of the haematopoietic stem cell niche. Lars Velten
12:10 – 13:15 Lunch
13:15 – 16:00 Tutorial: End-to-end workflow for single cell RNA-Seq analysis. Aaron Lun
15:00 – 15:30 Coffee break
16:00 – 17:00 Tutorial: Multi-Omics Factor Analysis. Britta Velten
17:00 End of the workshop

Monday 27 August 2018

SOUND Consortium Meeting (15’ presentation + 5’ discussion)

12:00 Registration and sandwich lunch
13:00 Welcome. Wolfgang Huber
13:10 – 13:30 WP 8 and 10. Martin Morgan (RPCCC)
13:30 – 13:50 WP 9. Alexander Bertram (BDD)
13:50 – 14:10 WP 4. Niko Beerenwinkel (ETH Zurich)
14:10 – 14:25 Break
14:25 – 14:45 WP 4. Susana Vinga (IDMEC)
14:45 – 15:05 WP 2. Daniele Biasci (UCAM)
15:05 – 15:35 Coffee break
15:35 – 15:55 WP 6. Mitch Levesque and Phil Cheng (USZ)
15:55 – 16:15 WP 5. Thorsten Zenz (DKFZ and USZ)
16:15 – 16:35 WP 1. Junyan Lu and Jennifer Hüllein (EMBL)
16:35 – 17:15 Discussion and wrap-up. All
17:15 – 19:00 Free time
19:00 Dinner (for the SOUND consortium and invited speakers only)

For inquiries related to the registration, scientific program and organisation, please contact Simone Bell, simone.bell(at)embl.de at European Molecular Biology Laboratory (EMBL), Heidelberg.